Renal colic and pyelonephritis
Differentiate uncomplicated stone disease from infection, sepsis and an infected obstructed system.
Flank pain / suspected stone flowchart
- Suspected stoneObservations, urinalysis, pregnancy test when relevant, FBC, CRP and U&E. Give analgesia: NSAID first line if suitable.
- Infection or high-risk obstruction?Fever/sepsis, anuria, AKI, bilateral obstruction, solitary/transplanted kidney or clinical deterioration.
- Yes — urgent UrologyCultures, current sepsis/antimicrobial pathway and immediate Urology discussion. Infected obstruction requires Urgent decompression.No — imageChoose imaging by age and pregnancy.
- Age under 16?
- Under 16 — SheffieldDiscuss with Sheffield paediatric service. NICE recommends ultrasound first; consider low-dose non-contrast CT only if uncertainty remains.Age 16+ — CT KUBUrgent low-dose non-contrast CT KUB within 24 hours. If pregnant, use ultrasound instead.
- ReassessDiscuss/admit for infection, AKI, anuria, solitary kidney, uncontrolled pain/vomiting or diagnostic uncertainty. Otherwise discharge with analgesia, safety-netting and stone follow-up.
Do not miss infected obstruction
Fever or sepsis with suspected upper-tract obstruction is a urological emergency. Start the current sepsis pathway, obtain cultures and blood tests, give antimicrobials according to the current DBTH policy, and contact Urology immediately for urgent source-control planning. Do not delay escalation while waiting for all results.
